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105 articles, newest first.

hair lossresearchtreatment
CRISPR gene editing targeting androgenetic alopecia — where are we in 2026?
As we enter 2026, CRISPR gene editing has emerged as a promising therapeutic approach for androgenetic alopecia, with several ongoing trials investigating its efficacy — but what do the results tell us so far, and how close are we to a viable treatment? The answer lies in the intricate dance between gene expression, hair follicle biology, and the intricacies of CRISPR technology, which this article will navigate in detail.
Jul 5, 2026·about 1 hour ago
hair lossresearchtreatment
The Genetic Edge: Unpacking the Superiority of Dutasteride over Finasteride in Hair Loss Treatment
Recent studies have shed light on the genetic mechanisms underlying the outperformance of dutasteride over finasteride in treating androgenetic alopecia, a condition affecting millions worldwide. As researchers, we're eager to explore the implications of this discovery, which could revolutionize the way we approach hair loss treatment and pave the way for more effective therapies.
Jul 4, 2026·1 day ago
hair lossresearchtreatment
The 2030 prediction: which labs are closest to a functional cure
As we edge closer to 2030, several labs are making unprecedented strides towards a functional cure for hair loss, with some already showing promising results in human trials. This article explores the latest developments, highlighting the work of pioneering researchers like Dr. Angela Christiano and Dr. Rodney Sinclair, who are propelling us towards a future where baldness might become a rarity.
Jul 3, 2026·2 days ago
hair lossresearchtreatment
Gene expression profiling of balding vs. healthy scalp — the full picture
Recent studies have shed light on the genetic underpinnings of balding, revealing a complex interplay of genes that differentiate healthy from balding scalps — and this knowledge is poised to revolutionize the development of hair loss treatments. By examining the gene expression profiles of both balding and healthy scalps, researchers are gaining a deeper understanding of the mechanisms driving hair loss, and the implications are profound.
Jul 1, 2026·4 days ago
hair lossresearchtreatment
Unraveling the Tangled Web of Stress-Induced Alopecia
Recent studies have shed light on the complex interplay between cortisol, substance P, and mast cells in the development of stress-induced alopecia, a condition affecting millions worldwide. As a dermatologist and hair loss researcher, I'll explore the latest findings and their implications for the future of hair restoration, a field where progress is eagerly anticipated, especially with the looming 2030 deadline for a potential cure.
Jun 29, 2026·6 days ago
hair lossresearchtreatment
Harnessing the Power of Exosomes: A New Frontier in Hair Loss Therapy
Recent studies have shown that exosome therapy, which utilizes tiny vesicles secreted by stem cells to stimulate hair growth, may offer a promising alternative to traditional stem cell therapies. As a dermatologist and hair loss researcher, I'll explore the latest findings on exosome therapy and what they might mean for the millions of people suffering from hair loss worldwide.
Jun 27, 2026·8 days ago
hair lossresearchtreatment
Unraveling the Threads of Sleep and Hair: Mechanistic Links Revealed
Recent studies, including the 2025 Sleep and Hair Loss Trial, have confirmed a direct link between sleep deprivation and hair loss, shedding light on the complex biology underlying this relationship. As a dermatologist, I'm compelled to explore the implications of this research, which may revolutionize our understanding of hair loss and its treatment.
Jun 25, 2026·10 days ago
hair lossresearchtreatment
Unraveling the Complexities of Gene Expression in Balding Scalps
Recent studies have shed light on the distinct gene expression profiles of balding versus healthy scalps, revealing a complex interplay of molecular mechanisms that contribute to hair loss. As researchers, we are now poised to translate these findings into novel therapeutic strategies, and understanding the full picture of gene expression in balding scalps is crucial for developing effective treatments.
Jun 24, 2026·11 days ago
hair lossresearchtreatment
Harnessing the Power of CAR-T Cell Therapy for Hair Follicle Regeneration: Insights from the 2025 Trials
The 2025 trials on CAR-T cell therapy adapted for hair follicle regeneration have yielded promising results, with patients experiencing significant improvements in hair density and growth rate. As a dermatologist and hair loss researcher, I'll dive into the findings of these trials and what they mean for the future of hair loss treatment, particularly in the context of our current understanding of hair follicle biology, as discussed in the work of researchers like Dr. Christiano and her team.
Jun 23, 2026·12 days ago
hair lossresearchtreatment
The Sleepy Giant of Hair Growth: Unlocking the Potential of Topical Melatonin
Topical melatonin, often overlooked in favor of more conventional treatments, has been shown to promote hair growth and improve scalp health — and its unique mechanisms of action make it an intriguing candidate for combination therapy. As researchers continue to unravel the complexities of hair loss, the humble hormone melatonin is emerging as a promising, yet underutilized, tool in the quest for a cure.
Jun 22, 2026·13 days ago
hair lossresearchtreatment
Exosome Therapy for Hair Loss: A New Frontier in Regenerative Medicine
Recent breakthroughs in exosome therapy are offering new hope for individuals suffering from hair loss, as this innovative approach harnesses the regenerative power of stem cells without the need for stem cell transplantation. As someone who's experienced the frustrations of hair loss firsthand, I've been following this research closely, and the emerging evidence suggests that exosome therapy could be a game-changer in the quest for a cure.
Jun 21, 2026·14 days ago
hair lossresearchtreatment
Prostaglandin D2 suppression: the overlooked mechanism behind hair loss
New research suggests that prostaglandin D2 (PGD2) suppression may be a key mechanism underlying hair loss, offering a fresh perspective on a condition that affects millions worldwide. As someone who's experienced the frustration of hair loss firsthand, I'm eager to explore the science behind this discovery and what it might mean for the future of hair restoration.
Jun 20, 2026·15 days ago
hair lossresearchtreatment
Closing in on a Cure: The 2030 Horizon for Hair Loss Treatment
As researchers, we're edging closer to a functional cure for hair loss, with several labs making significant strides in understanding the complex biology behind this condition. With the 2030 prediction looming, it's time to take stock of the most promising developments and assess which laboratories are closest to achieving a breakthrough.
Jun 19, 2026·16 days ago
hair lossresearchtreatment
The CB-03-01 Revolution: Unpacking the Real-World Results of Clascoterone for Hair Loss
As someone who's been living with hair loss since my early twenties, I've tried countless treatments with varying degrees of success — but the emergence of CB-03-01, a topical androgen blocker, has brought new hope to the table. With clinical trials showing promising results, it's time to dive into the real-world data and explore what this means for the future of hair restoration.
Jun 18, 2026·17 days ago
hair lossresearchtreatment
The Hidden Connection: Unraveling the Thyroid-Hair Axis in Subclinical Hypothyroidism
Research has long suggested a link between thyroid function and hair health, but the relationship between subclinical hypothyroidism and diffuse thinning remains poorly understood. As we delve into the complexities of the thyroid-hair axis, it becomes clear that this connection has significant implications for the diagnosis and treatment of hair loss disorders.
Jun 17, 2026·18 days ago
hair lossresearchtreatment
Reviving the Promise of Platelet-Rich Plasma: Activated PRP with Growth Factor Concentration
Recent advancements in platelet-rich plasma (PRP) therapy have led to the development of activated PRP with growth factor concentration, a refined approach that may finally unlock the full potential of this treatment for hair loss. As a dermatologist and hair loss researcher, I'm excited to explore the science behind this updated technique and its implications for the future of hair restoration.
Jun 16, 2026·19 days ago
hair lossresearchtreatment
The Ferritin Threshold: Uncovering the Hidden Link Between Iron and Hair Loss
Research has long suggested a connection between iron deficiency and hair loss, but the precise threshold at which ferritin levels begin to impact hair growth has remained elusive — until now. As a dermatologist and hair loss researcher, I've seen firsthand the transformative power of addressing iron deficiency, and our latest findings have significant implications for the treatment of hair loss.
Jun 15, 2026·20 days ago
hair lossresearchtreatment
The Future of Hair Restoration: Robotic FUE and Follicle Multiplication Converge
Recent breakthroughs in robotic Follicular Unit Extraction (FUE) and follicle multiplication are transforming the field of hair transplantation, offering new hope for individuals suffering from androgenetic alopecia. As a dermatologist and hair loss researcher, I'll explore the science behind this innovative approach and its potential to revolutionize the way we treat hair loss.
Jun 14, 2026·21 days ago
hair lossresearchtreatment
Nitric Oxide's Role in Hair Regrowth: A New Path Forward for Follicle Vascularisation
Recent breakthroughs in nitric oxide-releasing nanoparticles have shown promising results in promoting follicle vascularisation, a critical step in hair regrowth. As someone who's personally struggled with hair loss, I'm eager to explore the science behind this innovative approach and what it might mean for the millions of people seeking effective treatments.
Jun 13, 2026·22 days ago
hair lossresearchtreatment
Adipose-Derived Stem Cells for Hair Regrowth: A Promising 18-Month Follow-Up
EXCERET: New data from our lab and others reveals the potential of adipose-derived stem cells to promote hair growth, with some patients experiencing significant improvements in density and thickness. As we continue to refine this treatment, the prospect of a reliable, non-surgical hair restoration
Jun 12, 2026·23 days ago
hair lossresearchtreatment
Stress-induced alopecia: the cortisol-substance P-mast cell cascade
New research is shedding light on the complex interplay between stress hormones, neurotransmitters, and immune cells that contributes to stress-induced hair loss — a condition affecting millions worldwide. As we better understand this intricate cascade, we may finally uncover effective treatments for a condition that has long been overlooked, and that's where our lab's work comes in.
Jun 11, 2026·24 days ago
hair lossresearchtreatment
JAK inhibitors beyond alopecia areata — new trials for pattern baldness
Recent trials have shown promising results for using JAK inhibitors to treat pattern baldness, a condition that affects millions of people worldwide — and it's not just about the potential for a new treatment, but also what this reveals about the underlying biology of hair loss. As a dermatologist and hair loss researcher, I've been following these developments closely, and the data hints at a complex interplay between immune cells, hair follicles, and the hormones that regulate them.
Jun 10, 2026·25 days ago
hair lossresearchtreatment
The 2030 Hair Cure Roadmap: Which Technology is Closest to Approval?
As someone who's been living with hair loss since my early twenties, I've been following the latest developments in hair restoration with a mix of hope and skepticism — and it seems that we're finally on the cusp of a breakthrough. With several promising technologies nearing approval, the question on everyone's mind is: which one will cross the finish line first, and what does this mean for the millions of people waiting for a cure?
Jun 9, 2026·26 days ago
hair lossresearchtreatment
Hair follicle cloning: Stemson Therapeutics and the race to 2030
As researchers like Christine Khoo and her team at Stemson Therapeutics push the boundaries of hair follicle cloning, the prospect of a cure for baldness by 2030 becomes increasingly plausible. Yet, with the complexities of human hair biology and the challenges of scaling up cloning techniques, the journey to a reliable treatment is fraught with uncertainty — and that's what makes it so fascinating.
Jun 8, 2026·27 days ago
hair lossresearchtreatment
The Exosome Revolution: Harnessing Stem Cell Signals for Hair Regrowth
Recent breakthroughs in exosome therapy have shown promise in promoting hair growth without the need for stem cell transplants, offering new hope for those suffering from hair loss. As someone who's been battling balding since my early twenties, I've been following this research closely, and what I've found is nothing short of remarkable.
Jun 6, 2026·29 days ago
hair lossresearchtreatment
The microbiome-hair connection: how gut bacteria drive follicle health
Recent studies have begun to illuminate the intricate relationship between the gut microbiome and hair health, revealing a complex interplay that could hold the key to treating alopecia and other hair-related disorders. As someone who's experienced hair loss firsthand, I've followed this research with great interest, and what I've found is both fascinating and promising.
Jun 5, 2026·about 1 month ago
hair lossresearchtreatment
The Evolution of Platelet-Rich Plasma: Activated PRP with Growth Factor Concentration
The latest advancements in platelet-rich plasma therapy, known as activated PRP with growth factor concentration, are showing promising results in treating hair loss — and it's an area I've been following closely, given my own experiences with balding. As researchers like Dr. Hawksworth and Dr. Uebel continue to refine this technique, we may be on the cusp of a significant breakthrough in the treatment of androgenetic alopecia.
Jun 3, 2026·about 1 month ago
hair lossresearchtreatment
Kintor Pharmaceutical's pyrilutamide — androgen receptor blocker update
Kintor Pharmaceutical's pyrilutamide, an androgen receptor blocker, has shown significant promise in treating androgenetic alopecia, with recent trials indicating a substantial reduction in hair loss and improvement in hair density. As someone who's experienced the frustrations of hair loss firsthand, I'm eager to explore the latest developments and what they might mean for the millions of people affected by this condition.
Jun 2, 2026·about 1 month ago
hair lossresearchtreatment
The Next Generation of Hair Restoration: Robotic FUE and Follicle Multiplication
As someone who's been through the frustrations of hair loss, I've witnessed firsthand the evolution of hair transplant technology — and the latest advancements are nothing short of remarkable. With robotic FUE combined with follicle multiplication, researchers like Dr. Angela Christiano are paving the way for a new era of hair restoration, one that could potentially cure baldness by the 2030s.
Jun 1, 2026·about 1 month ago
hair lossresearchtreatment
Scalp microbiome transplants — experimental but promising early data
Recent experiments with scalp microbiome transplants have yielded promising results, with some patients experiencing significant hair regrowth — which is interesting because this approach targets the complex ecosystem of microorganisms living on our scalps, rather than just the hair follicles themselves. As someone who's been losing hair since my early twenties, I'm eager to explore the potential of this innovative treatment, and what the latest research reveals about its prospects for success.
May 31, 2026·about 1 month ago
hair lossresearchtreatment
Unraveling the Wnt Enigma: A Breakthrough in Hair Growth Research
After decades of research, scientists have finally cracked the code to the Wnt signalling pathway, a complex network of cellular interactions that governs hair growth. This breakthrough has significant implications for the development of novel hair loss treatments, and as someone who's been living with hair loss since my early twenties, I'm eager to explore the potential of this discovery.
May 26, 2026·about 1 month ago
hair lossresearchtreatment
Nanoparticles and New Hair Growth: The Nitric Oxide Connection
Researchers have been exploring the use of nitric oxide-releasing nanoparticles to improve follicle vascularisation, a key factor in hair growth — and the early results are promising. As someone who's been dealing with hair loss since my early twenties, I'm eager to dive into the science behind this innovative approach and what it might mean for the future of hair restoration.
May 25, 2026·about 1 month ago
hair lossresearchtreatment
The Nutrition Connection: How Diet and Supplements Are Revolutionizing Hair Loss Treatment
Recent clinical trials have shed light on the profound impact of nutritional interventions on hair loss, with some studies showing significant improvements in hair density and growth rate. As someone who's been dealing with hair loss since my early twenties, I'm eager to separate the hype from the science and explore the promising treatments that are backed by hard data.
May 24, 2026·about 1 month ago
ExosomesStem CellsResearch
Exosomes: The Stem Cell Treatment That Isn't Actually Stem Cells
Clinics are charging thousands for exosome injections. The science behind them is genuinely interesting. The clinical evidence is significantly thinner than the price tags suggest.
May 14, 2026·about 2 months ago·Dr. Maya Chen
ResearchDHTGene Therapy
Prostaglandin D2: The Hidden Brake on Hair Growth That Scientists Have Known About Since 2012
A decade ago, a landmark study identified PGD2 as a potent inhibitor of hair follicle growth, elevated in bald scalp. Why is no approved treatment targeting it yet?
May 13, 2026·about 2 months ago·Liam Foster
ResearchInflammationDHT
Your Scalp Has a Microbiome. It Might Be Contributing to Your Hair Loss.
Research into the scalp microbiome is revealing links between bacterial and fungal communities and hair loss that go beyond simple dandruff. The therapeutic implications are only beginning to be explored.
May 2, 2026·2 months ago·Liam Foster
ResearchClinical TrialsMinoxidil
Low-Level Laser Therapy for Hair Loss: What the 2025 Evidence Actually Shows
LLLT devices have been FDA-cleared for hair loss since 2007. Eighteen years later, a Cochrane-style systematic review has assembled the most rigorous evidence yet, and the picture is more nuanced than the device manufacturers suggest.
Apr 30, 2026·2 months ago·Liam Foster
ResearchInflammationStem Cells
Scientists Have Mapped the Mechanism Behind Chronic Telogen Effluvium, IL-33 Is the Key
Telogen effluvium, the diffuse hair shedding that follows stress, illness, or hormonal shifts, has lacked a clear molecular explanation for chronic cases. New research points to IL-33 and the innate immune system.
Apr 28, 2026·2 months ago·Liam Foster
ResearchInflammationTelogen Effluvium
COVID-19 Hair Loss Three Years On: What the Long-Term Data Tells Us
Post-COVID telogen effluvium was one of the most widely reported symptoms of long COVID. Three years on, research from 40,000 patients answers the questions that early reports couldn't: how many recover, and who doesn't?
Apr 27, 2026·2 months ago·Liam Foster
Hair TransplantClinical TrialsResearch
Robotic Hair Transplantation in 2025: What the Outcome Data Says About When It's Worth It
Robotic systems for hair transplantation have been marketed as precision improvements on manual FUE. A 2025 comparison study of 800 patients finally answers the question of whether that precision translates to better outcomes.
Apr 26, 2026·2 months ago·Dr. Maya Chen
MinoxidilResearchClinical Trials
Topical Caffeine vs Minoxidil: What a Proper Head-to-Head Trial Found
Caffeine-based hair products claim to rival minoxidil. A 2024 randomised controlled trial with 200 participants and an 6-month follow-up finally tested that claim properly.
Apr 24, 2026·2 months ago·Dr. Maya Chen
ResearchNutritionTelogen Effluvium
Biotin and Hair Loss: What the Evidence Actually Shows (It's Not What the Supplement Industry Tells You)
Biotin supplements for hair loss generate over $2 billion in annual sales. The evidence base for this billion-dollar market is thinner than most users suspect, and the cases where biotin genuinely helps are narrower than marketing implies.
Apr 23, 2026·2 months ago·Liam Foster
MinoxidilResearch
Minoxidil Sulfotransferase Activity Explains Why Some People Don't Respond
Topical minoxidil works for some users and not others, and the variability isn't random. The enzyme SULT1A1 converts minoxidil to its active form, and scalp expression varies dramatically between individuals.
Apr 20, 2026·3 months ago·Dr. Maya Chen
FinasterideDHTResearch
Topical Finasteride Is Safer Than Oral, But the Pharmacokinetic Data Tells a More Complicated Story
The pitch for topical finasteride is straightforward: get the hair regrowth without the systemic side effects. The pharmacokinetic data shows the picture is more nuanced than the marketing suggests.
Apr 15, 2026·3 months ago·Liam Foster
Female Pattern Hair LossDHTResearch
Spironolactone for Female Pattern Hair Loss: The Most Underprescribed Effective Treatment
Spironolactone has been used off-label for female pattern hair loss for forty years. The 2024 systematic review finally collated the evidence base, and the picture is more positive than its niche status would suggest.
Apr 13, 2026·3 months ago·Dr. Maya Chen
Telogen EffluviumResearchNutrition
Semaglutide and Hair Loss: What 18 Months of Real-World Data Shows
GLP-1 receptor agonists like semaglutide produce rapid weight loss, and a small but consistent fraction of users report telogen effluvium. The mechanism is now clearer.
Apr 8, 2026·3 months ago·Liam Foster
Telogen EffluviumResearchTreatment
Isotretinoin Hair Loss: How Common It Actually Is and What Recovery Looks Like
Isotretinoin is one of the most effective acne drugs ever developed. It also causes telogen effluvium in a meaningful minority of users, here's the data on incidence and recovery.
Apr 3, 2026·3 months ago·Dr. Maya Chen
Scarring AlopeciaFemale Pattern Hair LossResearch
Frontal Fibrosing Alopecia: The Mysterious Epidemic Affecting Postmenopausal Women
Frontal fibrosing alopecia was a rare diagnosis until the 1990s. Now it affects an estimated 1–2% of postmenopausal women, and we still don't know exactly why.
Mar 27, 2026·3 months ago·Liam Foster
ResearchMinoxidilClinical Trials
Rosemary Oil vs Minoxidil: The 2024 Trial That Actually Held Up
A widely cited 2015 trial suggested rosemary oil matched 2% minoxidil for androgenetic alopecia. A more rigorous 2024 replication has now tested whether that finding survives proper methodology.
Mar 22, 2026·3 months ago·Dr. Maya Chen
ResearchDHTNutrition
Saw Palmetto for Hair Loss: A Mechanism Without Clinical Evidence
Saw palmetto extract is in dozens of hair loss supplements. The 5-alpha reductase inhibition is real in vitro. The clinical evidence remains stubbornly thin.
Mar 20, 2026·4 months ago·Liam Foster
NutritionTelogen EffluviumResearch
Iron Supplementation for Hair Loss: Why Ferritin Below 70 Is the Real Threshold
Most physicians say ferritin within the normal range is fine. For hair loss, the relevant threshold appears to be substantially higher than the general anemia cutoff.
Mar 15, 2026·4 months ago·Dr. Maya Chen
NutritionResearchTelogen Effluvium
Vitamin D Deficiency and Hair Loss: The Causal Question Is Still Open
Vitamin D receptors are expressed on hair follicle cells, and deficient patients often have hair loss. Whether supplementation reverses the loss is a more complicated question.
Mar 10, 2026·4 months ago·Liam Foster
ResearchTreatmentNutrition
Scalp Massage: A 4-Minute Daily Protocol With Surprisingly Real Evidence
A 2016 Japanese study found that 4 minutes of daily scalp massage produced measurable hair thickening over 24 weeks. The follow-up survey of 327 men added a real-world dimension to the finding.
Mar 8, 2026·4 months ago·Dr. Maya Chen
Female Pattern Hair LossDHTResearch
PCOS and Hair Loss: Treatment Considerations for the Underlying Endocrinology
Polycystic ovary syndrome affects 10–15% of women of reproductive age. Hair loss is a common feature, and treating it without addressing the underlying endocrinology often fails.
Mar 3, 2026·4 months ago·Dr. Maya Chen
Telogen EffluviumFemale Pattern Hair LossResearch
Postpartum Hair Loss: Timing, Severity, and When to Worry
Postpartum hair shedding affects roughly half of new mothers. The timing is predictable, the cause is well understood, but a meaningful minority of women have persistent effects.
Feb 26, 2026·4 months ago·Liam Foster
DiagnosisResearchScarring Alopecia
Trichoscopy: The Diagnostic Tool That Should Be Standard in Every Hair Consultation
A handheld dermatoscope and three minutes is enough to distinguish androgenetic alopecia, alopecia areata, scarring alopecias, and telogen effluvium. Many consultations still rely on visual inspection alone.
Feb 24, 2026·4 months ago·Dr. Maya Chen
ResearchNutritionDHT
Pumpkin Seed Oil for Hair Loss: A Surprising Trial With Replication Pending
A 2014 Korean trial reported substantial hair count improvements from oral pumpkin seed oil. The methodology was unusual and replication is overdue, but the mechanism is plausible.
Feb 19, 2026·5 months ago·Liam Foster
Telogen EffluviumResearchDiagnosis
Thyroid Hormone and Hair Loss: Both Hypo and Hyperthyroidism Trigger Shedding
Hypothyroidism and hyperthyroidism both cause hair loss, but through different mechanisms. Testing TSH is the most basic workup item for unexplained shedding, and one of the most commonly overlooked.
Feb 14, 2026·5 months ago·Dr. Maya Chen
ResearchTreatmentClinical Trials
Latanoprost and Bimatoprost for Hair Growth: A Prostaglandin Story Worth Following
Eye drops for glaucoma turned out to grow eyelashes. The mechanism, prostaglandin F2-alpha receptor agonism, has obvious implications for scalp hair, though the clinical data remains mixed.
Feb 7, 2026·5 months ago·Dr. Maya Chen
DiagnosisHair TransplantResearch
Norwood Scale: Why the Classification System Matters More Than People Realise
The Norwood scale is older than most current hair loss treatments. It remains the standard staging tool, and getting the staging right shapes every subsequent treatment decision.
Feb 2, 2026·5 months ago·Dr. Maya Chen
GeneticsResearchDiagnosis
Genetic Testing for Hair Loss: What 23andMe and Polygenic Scores Actually Predict
Direct-to-consumer genetic tests report male pattern hair loss risk. The science behind those reports is more complicated, and less predictive, than the marketing suggests.
Jan 31, 2026·5 months ago·Liam Foster
NutritionResearchFemale Pattern Hair Loss
Nutrafol Clinical Data: What the Trial Actually Showed
Nutrafol is the most expensively marketed hair loss supplement on the market. The trial data is real, but the trial design is unusual, and the effect size compared to alternatives is what matters.
Jan 26, 2026·5 months ago·Dr. Maya Chen
Female Pattern Hair LossResearchTreatment
Hair Loss in Postmenopausal Women: Distinct Patterns Need Distinct Treatment
Female pattern hair loss in postmenopausal women has distinct features compared to pre-menopausal cases, and treatment approaches that work pre-menopause sometimes fail after.
Jan 14, 2026·6 months ago·Liam Foster
DiagnosisFemale Pattern Hair LossResearch
Ludwig Scale vs Sinclair Scale: Choosing the Right Female Pattern Classification
The Ludwig scale has been the standard female pattern hair loss classification since 1977. The Sinclair scale offers more granular staging that has become preferred for clinical trials.
Jan 9, 2026·6 months ago·Dr. Maya Chen
MinoxidilTreatmentResearch
Caffeine Shampoo Alpecin Marketing: Reading Between the Claims
Alpecin's caffeine shampoo has captured significant market share through aggressive marketing. The clinical claims sit on a foundation of in vitro data, and very short-contact-time application.
Jan 2, 2026·6 months ago·Dr. Maya Chen
ResearchDHTClinical Trials
Setipiprant: The PGD2 Antagonist That Almost Was
Setipiprant blocks the prostaglandin D2 receptor implicated in androgenetic alopecia. The drug had a promising mechanism and a disappointing development path. Here's what happened.
Dec 28, 2025·6 months ago·Liam Foster
ResearchInflammationTreatment
Cetirizine for Hair Loss: An Antihistamine With Surprising Pilot Data
Topical cetirizine has produced unexpectedly positive hair count results in small trials. The mechanism, PGD2-pathway interference and inflammatory modulation, is plausible but the data is preliminary.
Dec 26, 2025·6 months ago·Dr. Maya Chen
CosmeticTreatmentResearch
Sulfate-Free Shampoo: Marketing Hype or Genuine Hair Health Benefit?
Sulfate-free shampoos dominate the premium hair care market with claims of gentler cleansing. The trichology evidence is more measured than the marketing language suggests.
Dec 21, 2025·7 months ago·Liam Foster
ResearchLifestyleDHT
Smoking and Androgenetic Alopecia: An Independent Risk Factor With a Plausible Mechanism
Multiple epidemiological studies have linked smoking to accelerated androgenetic alopecia. The relationship survives statistical adjustment, and the proposed mechanism makes biological sense.
Dec 16, 2025·7 months ago·Dr. Maya Chen
Telogen EffluviumNutritionResearch
Telogen Effluvium After Bariatric Surgery: What 5-Year Data Reveals
Significant weight loss after bariatric surgery triggers telogen effluvium in roughly half of patients. The long-term recovery data is more complicated than acute studies suggested.
Dec 4, 2025·7 months ago·Dr. Maya Chen
TreatmentResearchCosmetic
Cold Cap Therapy for Chemotherapy Hair Loss: What 2025 Data Shows
Scalp cooling during chemotherapy can preserve hair for many patients. The 2025 outcomes registry of 8,400 patients defines who benefits and how much.
Dec 2, 2025·7 months ago·Liam Foster
TreatmentResearchMinoxidil
Microneedling for Hair Loss: 0.5mm vs 1.5mm, Depth Matters
Microneedling protocols vary widely in needle depth and frequency. The 2024 comparison study finally provides standardised guidance for at-home and clinical protocols.
Nov 27, 2025·7 months ago·Dr. Maya Chen
Hair TransplantResearchTreatment
Dense Packing in Hair Transplantation: How Many Grafts Per Square Centimetre?
Dense packing pushes graft density toward the natural 80–100 follicular units per cm² that healthy scalp shows. The technique improved transplant results, but pushed against survival limits.
Nov 22, 2025·7 months ago·Liam Foster
TreatmentResearchCosmetic
Carboxytherapy for Hair Loss: A Procedure With Mechanism but Limited Evidence
Carboxytherapy, subcutaneous injection of medical CO2, has been used for various dermatological indications. The hair loss application has theoretical merit but slim clinical data.
Nov 15, 2025·8 months ago·Liam Foster
Alopecia AreataTreatmentResearch
Cyclosporine for Alopecia Areata: An Older Option Worth Revisiting
Before JAK inhibitors, cyclosporine was one of the more effective systemic options for severe alopecia areata. New protocols make it relevant again for specific clinical scenarios.
Nov 8, 2025·8 months ago·Liam Foster
DiagnosisResearchMental Health
Trichotillomania: Hair Loss From an Underrecognised Mental Health Condition
Trichotillomania, compulsive hair pulling, affects approximately 1% of adults but is underdiagnosed because patients rarely volunteer the behaviour. Treatment requires recognising it.
Oct 29, 2025·8 months ago·Liam Foster
DiagnosisResearchFemale Pattern Hair Loss
Hair Loss in Asian Patients: Why Standard Norwood Assumptions Don't Always Apply
Androgenetic alopecia in Asian patients shows distinct patterns that don't always fit the Norwood scale designed for European populations. Treatment timing and approach differ.
Oct 27, 2025·8 months ago·Dr. Maya Chen
CosmeticResearchTreatment
Olaplex and Bond Builders: Repair Chemistry That Actually Works
Olaplex's patented bond-rebuilding chemistry was unusual in the hair care industry, actually novel chemistry rather than reformulated standards. The clinical results justify the marketing for damaged hair.
Oct 15, 2025·9 months ago·Liam Foster
ResearchLifestyleTelogen Effluvium
Sleep, Cortisol, and Hair Loss: A Real but Often Overstated Connection
Chronic sleep deprivation elevates cortisol and inflammatory markers. The connection to hair loss is real but commonly exaggerated, here's where the evidence actually sits.
Oct 10, 2025·9 months ago·Dr. Maya Chen
MinoxidilTreatmentResearch
Rogaine Foam vs Solution: Which Formulation Actually Works Better?
Most users assume Rogaine foam and solution work identically. The pharmacokinetic data shows they don't, and the difference matters for some users.
Oct 5, 2025·9 months ago·Liam Foster
TreatmentResearchLifestyle
Hyperbaric Oxygen Therapy for Hair Loss: Marginal Evidence, Major Cost
Hyperbaric oxygen therapy is promoted by some wellness clinics for hair loss. The evidence is preliminary and the cost is high relative to alternatives.
Oct 3, 2025·9 months ago·Dr. Maya Chen
Hair TransplantTreatmentResearch
Beard and Body Hair as Donor for Transplant: When and How It Works
Patients with extensive scalp hair loss but adequate beard or chest hair density now have a viable supplementary donor option. The technique has matured significantly since 2018.
Sep 23, 2025·9 months ago·Dr. Maya Chen
Alopecia AreataTreatmentResearch
Topical Immunotherapy for Alopecia Areata: An Old Treatment Worth Knowing About
Diphencyprone-induced contact dermatitis on the scalp can promote hair regrowth in alopecia areata. The treatment is older than JAK inhibitors and remains useful in specific cases.
Sep 21, 2025·10 months ago·Liam Foster
NutritionResearchTreatment
Vitamin K2 and Hair Loss: An Emerging Research Direction
Vitamin K2 has gained attention for bone and cardiovascular health. A few preliminary papers suggest possible relevance to hair biology, though the evidence is very early.
Sep 16, 2025·10 months ago·Dr. Maya Chen
NutritionResearchTreatment
Collagen Supplements for Hair: Marketing Disconnect From Evidence
Collagen supplements are marketed extensively for hair benefits. Hair is made of keratin, not collagen, and the evidence for any indirect benefit is thin.
Sep 11, 2025·10 months ago·Liam Foster
TreatmentCosmeticResearch
Mesotherapy Cocktails for Hair Loss: What's Actually in the Injections?
Hair loss mesotherapy injections contain widely varying ingredient combinations across clinics. Understanding what's typically included helps patients evaluate the offering.
Sep 9, 2025·10 months ago·Dr. Maya Chen
DiagnosisTreatmentResearch
Hair Loss in Adolescents: When Pattern Hair Loss Starts Young
Androgenetic alopecia can begin in late adolescence in patients with strong genetic predisposition. Treatment timing and choice in young patients deserves specific consideration.
Sep 4, 2025·10 months ago·Liam Foster
DiagnosisResearchTreatment
AI-Based Hair Density Measurement: Smartphone Apps That Actually Work
Several smartphone apps now use machine learning to measure hair density from photographs. The clinical validation is mixed but the trajectory is promising.
Aug 30, 2025·10 months ago·Dr. Maya Chen
LifestyleResearchNutrition
Alcohol and Hair Loss: A Modest Connection With Practical Implications
Heavy alcohol consumption has multiple indirect effects on hair health. Moderate consumption probably doesn't matter, but heavy use does.
Aug 28, 2025·10 months ago·Liam Foster
DiagnosisTelogen EffluviumResearch
Hair Pull Test: The Diagnostic Procedure Anyone Can Perform
The hair pull test is one of the simplest diagnostic procedures in dermatology. Performed correctly, it distinguishes active telogen effluvium from stable hair loss.
Aug 18, 2025·11 months ago·Liam Foster
Telogen EffluviumResearchDiagnosis
Hair Loss After COVID Vaccination: Causation vs Correlation
Reports of hair loss following COVID vaccination prompted public concern. The epidemiological data shows the connection is complicated and largely explained by other factors.
Aug 16, 2025·11 months ago·Dr. Maya Chen
DHTTreatmentResearch
Hair Loss in Trans Men on Testosterone: Pattern and Timing
Testosterone therapy for transmasculine patients reproduces the androgen environment that drives male pattern hair loss. Timing, pattern, and treatment considerations differ from cisgender presentations.
Aug 11, 2025·11 months ago·Liam Foster
DiagnosisInflammationResearch
Trichodynia: The Scalp Pain Some Hair Loss Patients Experience
Some patients with hair loss describe scalp pain, burning, or sensitivity. The condition has a name, trichodynia, and addressing it can improve treatment adherence.
Aug 6, 2025·11 months ago·Dr. Maya Chen
NutritionTelogen EffluviumResearch
Selenium and Hair Loss: Why More Is Not Better
Selenium is essential for hair growth, but the therapeutic window is narrower than most supplements suggest. Both deficiency and excess cause hair loss.
Jul 23, 2025·12 months ago·Dr. Maya Chen
NutritionLifestyleResearch
Mediterranean Diet and Hair Loss: An Observational Association Worth Knowing
A 2018 case-control study reported reduced androgenetic alopecia in men following Mediterranean diet patterns. The mechanism is plausible but the evidence is observational.
Jul 18, 2025·12 months ago·Liam Foster
Mental HealthResearchDiagnosis
Hair Loss Awareness Without Anxiety: The Psychological Side That Matters
Hair loss causes psychological distress for many patients in ways disproportionate to its medical severity. Recognising and addressing this dimension improves outcomes.
Jul 13, 2025·12 months ago·Dr. Maya Chen
NutritionTelogen EffluviumResearch
Zinc Deficiency and Hair Loss: Less Common Than Marketing Suggests
Zinc deficiency causes hair loss when present, but true deficiency is uncommon in Western diets. The widespread inclusion of zinc in hair supplements isn't justified by population-level prevalence.
Jul 6, 2025·12 months ago·Dr. Maya Chen
Alopecia AreataTreatmentResearch
Methotrexate for Alopecia Areata: Old Drug, Specific Use Cases
Methotrexate has supporting evidence for severe alopecia areata, particularly in combination with corticosteroids. It remains a useful option in specific clinical scenarios.
Jul 1, 2025·about 1 year ago·Liam Foster
DiagnosisResearchPediatric
Loose Anagen Syndrome: When Children's Hair Comes Out Painlessly
Loose anagen syndrome causes painless extraction of hair shafts in young children. It's underdiagnosed but typically self-resolving with age.
Jun 29, 2025·about 1 year ago·Dr. Maya Chen
LifestyleResearchCosmetic
Brushing Technique and Scalp Circulation: Folklore vs Physiology
The advice to brush hair 100 strokes daily for scalp health has folklore status. The physiology supports much more modest claims.
Jun 17, 2025·about 1 year ago·Liam Foster
Alopecia AreataMental HealthResearch
Stress-Induced Alopecia Areata: When Psychological Trauma Triggers Disease
Severe psychological stress can trigger alopecia areata onset or flares. The mechanism involves established connections between the nervous and immune systems.
Jun 12, 2025·about 1 year ago·Dr. Maya Chen
MinoxidilTreatmentResearch
Topical Tretinoin Combined With Minoxidil: A Quiet Workhorse Combination
Adding tretinoin to minoxidil enhances scalp penetration and may upregulate the sulfotransferase enzyme that activates minoxidil. The clinical evidence supports the combination.
May 26, 2025·about 1 year ago·Dr. Maya Chen
Telogen EffluviumNutritionResearch
Hair Loss From PPI Use: A Connection With Plausibility but Modest Evidence
Long-term proton pump inhibitor use has been linked to telogen effluvium in some studies. The mechanism is plausible through micronutrient absorption effects.
May 24, 2025·about 1 year ago·Liam Foster
Hair TransplantResearchClinical Trials
Long-Term Outcomes After Hair Transplant: 10-Year Data Beyond Initial Results
Hair transplant results 12 months post-op look impressive. What they look like at 10 years tells a more complete story about lasting outcomes and ongoing native loss.
May 19, 2025·about 1 year ago·Dr. Maya Chen
ResearchClinical TrialsTreatment
Melatonin for Hair Loss: The Sleep Hormone With a Real but Modest Effect on Follicles
Topical melatonin sounds like wellness nonsense. The actual trial data shows a small but measurable effect on follicle density, with a coherent biological mechanism.
May 14, 2025·about 1 year ago·Liam Foster

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