ResearchTreatment7 months ago

Latanoprost and Bimatoprost for Hair Growth: A Prostaglandin Story Worth Following

Eye drops for glaucoma turned out to grow eyelashes. The mechanism, prostaglandin F2-alpha receptor agonism, has obvious implications for scalp hair, though the clinical data remains mixed.

Dr. Maya

17.5k views3 min read

DiagnosisHair Transplant7 months ago

Norwood Scale: Why the Classification System Matters More Than People Realise

The Norwood scale is older than most current hair loss treatments. It remains the standard staging tool, and getting the staging right shapes every subsequent treatment decision.

Dr. Maya

4.7k views3 min read

GeneticsResearch7 months ago

Genetic Testing for Hair Loss: What 23andMe and Polygenic Scores Actually Predict

Direct-to-consumer genetic tests report male pattern hair loss risk. The science behind those reports is more complicated, and less predictive, than the marketing suggests.

Liam Foster,

8.7k views3 min read

NutritionResearch7 months ago

Nutrafol Clinical Data: What the Trial Actually Showed

Nutrafol is the most expensively marketed hair loss supplement on the market. The trial data is real, but the trial design is unusual, and the effect size compared to alternatives is what matters.

Dr. Maya

9.5k views3 min read

TreatmentMinoxidil7 months ago

Compounded Topical Formulations: The Pharmacy Workaround That Has Quietly Reshaped Treatment

Compounding pharmacies have become a significant force in hair loss treatment, producing custom topical formulations that combine multiple active ingredients in single products.

Liam Foster,

12.4k views3 min read

Hair TransplantTreatment7 months ago

Hair Transplant Turkey: Cost Savings vs Quality Trade-offs

Turkey now performs more hair transplants than any other country worldwide. The cost advantage is genuine, but the quality variance is substantial, and patients need to understand both.

Dr. Maya

8.8k views3 min read

Female Pattern Hair LossResearch8 months ago

Hair Loss in Postmenopausal Women: Distinct Patterns Need Distinct Treatment

Female pattern hair loss in postmenopausal women has distinct features compared to pre-menopausal cases, and treatment approaches that work pre-menopause sometimes fail after.

Liam Foster,

12.7k views3 min read

DiagnosisFemale Pattern Hair Loss8 months ago

Ludwig Scale vs Sinclair Scale: Choosing the Right Female Pattern Classification

The Ludwig scale has been the standard female pattern hair loss classification since 1977. The Sinclair scale offers more granular staging that has become preferred for clinical trials.

Dr. Maya

11.1k views3 min read

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CosmeticTreatment8 months ago

Hair Fibre Concealers: Toppik, Caboki, and What Actually Works

Keratin hair fibres are the most cost-effective cosmetic treatment for mild hair loss. Different brands use different fibre materials with substantially different performance characteristics.

Liam Foster,

14.9k views3 min read

MinoxidilTreatment8 months ago

Caffeine Shampoo Alpecin Marketing: Reading Between the Claims

Alpecin's caffeine shampoo has captured significant market share through aggressive marketing. The clinical claims sit on a foundation of in vitro data, and very short-contact-time application.

Dr. Maya

10.6k views3 min read

ResearchDHT8 months ago

Setipiprant: The PGD2 Antagonist That Almost Was

Setipiprant blocks the prostaglandin D2 receptor implicated in androgenetic alopecia. The drug had a promising mechanism and a disappointing development path. Here's what happened.

Liam Foster,

13.3k views3 min read

ResearchInflammation8 months ago

Cetirizine for Hair Loss: An Antihistamine With Surprising Pilot Data

Topical cetirizine has produced unexpectedly positive hair count results in small trials. The mechanism, PGD2-pathway interference and inflammatory modulation, is plausible but the data is preliminary.

Dr. Maya

3.0k views3 min read

CosmeticTreatment8 months ago

Sulfate-Free Shampoo: Marketing Hype or Genuine Hair Health Benefit?

Sulfate-free shampoos dominate the premium hair care market with claims of gentler cleansing. The trichology evidence is more measured than the marketing language suggests.

Liam Foster,

12.9k views3 min read

ResearchLifestyle9 months ago

Smoking and Androgenetic Alopecia: An Independent Risk Factor With a Plausible Mechanism

Multiple epidemiological studies have linked smoking to accelerated androgenetic alopecia. The relationship survives statistical adjustment, and the proposed mechanism makes biological sense.

Dr. Maya

10.4k views3 min read

TreatmentCosmetic9 months ago

Hair Systems and Toppers: When Wearing Hair Makes More Sense Than Growing It

Modern hair systems are unrecognisable from the toupées of the 1980s. For patients with extensive hair loss, they offer instant, high-quality cosmetic transformation that other approaches can't match.

Liam Foster,

7.9k views3 min read

Alopecia AreataJAK Inhibitors9 months ago

Alopecia Areata: Beyond JAK Inhibitors, What Else Is in the Pipeline

JAK inhibitors transformed alopecia areata treatment, but they're not the end of the story. Several other immune-modulating approaches are advancing through clinical trials.

Dr. Maya

15.0k views3 min read

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Telogen EffluviumNutrition9 months ago

Telogen Effluvium After Bariatric Surgery: What 5-Year Data Reveals

Significant weight loss after bariatric surgery triggers telogen effluvium in roughly half of patients. The long-term recovery data is more complicated than acute studies suggested.

Dr. Maya

8.0k views3 min read

TreatmentResearch9 months ago

Cold Cap Therapy for Chemotherapy Hair Loss: What 2025 Data Shows

Scalp cooling during chemotherapy can preserve hair for many patients. The 2025 outcomes registry of 8,400 patients defines who benefits and how much.

Liam Foster,

8.5k views3 min read

TreatmentResearch9 months ago

Microneedling for Hair Loss: 0.5mm vs 1.5mm, Depth Matters

Microneedling protocols vary widely in needle depth and frequency. The 2024 comparison study finally provides standardised guidance for at-home and clinical protocols.

Dr. Maya

9.0k views3 min read

Hair TransplantResearch9 months ago

Dense Packing in Hair Transplantation: How Many Grafts Per Square Centimetre?

Dense packing pushes graft density toward the natural 80 to 100 follicular units per cm² that healthy scalp shows. The technique improved transplant results, but pushed against survival limits.

Liam Foster,

11.9k views3 min read

Hair TransplantCosmetic9 months ago

Hairline Design in Hair Transplantation: The Art That Determines Natural Results

The single most important determinant of natural-looking hair transplant results is the hairline design. Get it wrong and no surgical technique can rescue it.

Dr. Maya

3.3k views3 min read

TreatmentResearch10 months ago

Carboxytherapy for Hair Loss: A Procedure With Mechanism but Limited Evidence

Carboxytherapy, subcutaneous injection of medical CO2, has been used for various dermatological indications. The hair loss application has theoretical merit but slim clinical data.

Liam Foster,

11.7k views3 min read

Hair TransplantTreatment10 months ago

Long Hair FUE: The Technique That Eliminates the Post-Op Buzz Cut

Standard FUE requires shaving the donor area. Long Hair FUE preserves donor hair length, eliminating one of the major lifestyle obstacles to hair transplantation.

Dr. Maya

10.0k views3 min read

Alopecia AreataTreatment10 months ago

Cyclosporine for Alopecia Areata: An Older Option Worth Revisiting

Before JAK inhibitors, cyclosporine was one of the more effective systemic options for severe alopecia areata. New protocols make it relevant again for specific clinical scenarios.

Liam Foster,

5.6k views3 min read

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Scarring AlopeciaCosmetic10 months ago

Traction Alopecia: Prevention Matters Because Treatment Doesn't Work Well

Traction alopecia from tight hairstyles is one of the few common forms of hair loss that's almost entirely preventable. Once established, treatment options are limited.

Dr. Maya

9.6k views3 min read

DiagnosisResearch10 months ago

Trichotillomania: Hair Loss From an Underrecognised Mental Health Condition

Trichotillomania, compulsive hair pulling, affects approximately 1% of adults but is underdiagnosed because patients rarely volunteer the behaviour. Treatment requires recognising it.

Liam Foster,

11.8k views3 min read

DiagnosisResearch10 months ago

Hair Loss in Asian Patients: Why Standard Norwood Assumptions Don't Always Apply

Androgenetic alopecia in Asian patients shows distinct patterns that don't always fit the Norwood scale designed for European populations. Treatment timing and approach differ.

Dr. Maya

3.5k views3 min read

Scarring AlopeciaDiagnosis10 months ago

Hair Loss Patterns in African Descent: CCCA and Distinct Considerations

Central centrifugal cicatricial alopecia is the most common scarring alopecia in women of African descent. It's underdiagnosed and treatment opportunities are time-limited.

Liam Foster,

6.5k views3 min read

DHTFinasteride11 months ago

Dutasteride vs Finasteride for Androgenetic Alopecia: When to Choose Each

Dutasteride blocks both 5-alpha reductase isoforms; finasteride blocks only type 2. The clinical comparison shows dutasteride wins on efficacy and loses on side effect profile.

Dr. Maya

10.3k views3 min read

CosmeticResearch11 months ago

Olaplex and Bond Builders: Repair Chemistry That Actually Works

Olaplex's patented bond-rebuilding chemistry was unusual in the hair care industry, actually novel chemistry rather than reformulated standards. The clinical results justify the marketing for damaged hair.

Liam Foster,

3.9k views3 min read