Topic

DHT

9 articles, newest first.

FinasterideDHTResearch
Topical Finasteride Is Safer Than Oral, But the Pharmacokinetic Data Tells a More Complicated Story
The pitch for topical finasteride is straightforward: get the hair regrowth without the systemic side effects. The pharmacokinetic data shows the picture is more nuanced than the marketing suggests.
Apr 15, 2026·4 months ago·Liam Foster, MSc
Female Pattern Hair LossDHTResearch
Spironolactone for Female Pattern Hair Loss: The Most Underprescribed Effective Treatment
Spironolactone has been used off-label for female pattern hair loss for forty years. The 2024 systematic review finally collated the evidence base, and the picture is more positive than its niche status would suggest.
Apr 13, 2026·4 months ago·Dr. Maya Chen, MD, PhD
ResearchDHTNutrition
Saw Palmetto for Hair Loss: A Mechanism Without Clinical Evidence
Saw palmetto extract is in dozens of hair loss supplements. The 5-alpha reductase inhibition is real in vitro. The clinical evidence remains stubbornly thin.
Mar 20, 2026·5 months ago·Liam Foster, MSc
Female Pattern Hair LossDHTResearch
PCOS and Hair Loss: Treatment Considerations for the Underlying Endocrinology
Polycystic ovary syndrome affects 10 to 15% of women of reproductive age. Hair loss is a common feature, and treating it without addressing the underlying endocrinology often fails.
Mar 3, 2026·6 months ago·Dr. Maya Chen, MD, PhD
ResearchNutritionDHT
Pumpkin Seed Oil for Hair Loss: A Surprising Trial With Replication Pending
A 2014 Korean trial reported substantial hair count improvements from oral pumpkin seed oil. The methodology was unusual and replication is overdue, but the mechanism is plausible.
Feb 19, 2026·6 months ago·Liam Foster, MSc
ResearchDHTClinical Trials
Setipiprant: The PGD2 Antagonist That Almost Was
Setipiprant blocks the prostaglandin D2 receptor implicated in androgenetic alopecia. The drug had a promising mechanism and a disappointing development path. Here's what happened.
Dec 28, 2025·8 months ago·Liam Foster, MSc
ResearchLifestyleDHT
Smoking and Androgenetic Alopecia: An Independent Risk Factor With a Plausible Mechanism
Multiple epidemiological studies have linked smoking to accelerated androgenetic alopecia. The relationship survives statistical adjustment, and the proposed mechanism makes biological sense.
Dec 16, 2025·8 months ago·Dr. Maya Chen, MD, PhD
DHTFinasterideTreatment
Dutasteride vs Finasteride for Androgenetic Alopecia: When to Choose Each
Dutasteride blocks both 5-alpha reductase isoforms; finasteride blocks only type 2. The clinical comparison shows dutasteride wins on efficacy and loses on side effect profile.
Oct 17, 2025·10 months ago·Dr. Maya Chen, MD, PhD
DHTTreatmentResearch
Hair Loss in Trans Men on Testosterone: Pattern and Timing
Testosterone therapy for transmasculine patients reproduces the androgen environment that drives male pattern hair loss. Timing, pattern, and treatment considerations differ from cisgender presentations.
Aug 11, 2025·about 1 year ago·Liam Foster, MSc

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DHT

Topical Finasteride Is Safer Than Oral, But the Pharmacokinetic Data Tells a More Complicated Story

Spironolactone for Female Pattern Hair Loss: The Most Underprescribed Effective Treatment

Saw Palmetto for Hair Loss: A Mechanism Without Clinical Evidence

PCOS and Hair Loss: Treatment Considerations for the Underlying Endocrinology

Pumpkin Seed Oil for Hair Loss: A Surprising Trial With Replication Pending

Setipiprant: The PGD2 Antagonist That Almost Was

Smoking and Androgenetic Alopecia: An Independent Risk Factor With a Plausible Mechanism

Dutasteride vs Finasteride for Androgenetic Alopecia: When to Choose Each

Hair Loss in Trans Men on Testosterone: Pattern and Timing