Topic

clinical trials

25 articles, newest first.

hair lossresearchtreatment
Harnessing the Power of CAR-T Cell Therapy for Hair Follicle Regeneration: Insights from the 2025 Trials
The 2025 trials on CAR-T cell therapy adapted for hair follicle regeneration have yielded promising results, with patients experiencing significant improvements in hair density and growth rate. As a dermatologist and hair loss researcher, I'll dive into the findings of these trials and what they mean for the future of hair loss treatment, particularly in the context of our current understanding of hair follicle biology, as discussed in the work of researchers like Dr. Christiano and her team.
Jun 23, 2026·12 days ago
hair lossresearchtreatment
The Hidden Connection: Unraveling the Thyroid-Hair Axis in Subclinical Hypothyroidism
Research has long suggested a link between thyroid function and hair health, but the relationship between subclinical hypothyroidism and diffuse thinning remains poorly understood. As we delve into the complexities of the thyroid-hair axis, it becomes clear that this connection has significant implications for the diagnosis and treatment of hair loss disorders.
Jun 17, 2026·18 days ago
hair lossresearchtreatment
JAK inhibitors beyond alopecia areata — new trials for pattern baldness
Recent trials have shown promising results for using JAK inhibitors to treat pattern baldness, a condition that affects millions of people worldwide — and it's not just about the potential for a new treatment, but also what this reveals about the underlying biology of hair loss. As a dermatologist and hair loss researcher, I've been following these developments closely, and the data hints at a complex interplay between immune cells, hair follicles, and the hormones that regulate them.
Jun 10, 2026·25 days ago
hair lossresearchtreatment
The Nutrition Connection: How Diet and Supplements Are Revolutionizing Hair Loss Treatment
Recent clinical trials have shed light on the profound impact of nutritional interventions on hair loss, with some studies showing significant improvements in hair density and growth rate. As someone who's been dealing with hair loss since my early twenties, I'm eager to separate the hype from the science and explore the promising treatments that are backed by hard data.
May 24, 2026·about 1 month ago
JAK InhibitorsClinical TrialsAlopecia Areata
Ritlecitinib Changed Everything, But Not For the Reason Most People Think
The FDA approval of ritlecitinib for alopecia areata in 2023 was framed as a win for one autoimmune condition. The researchers who understand where this drug family is going know it's something bigger.
May 16, 2026·about 2 months ago·Dr. Maya Chen
Stem Cells2030 CureClinical Trials
Hair Follicle Cloning Is Closer Than You Think, And Further Than You Hope
Stemson Therapeutics completed its first human safety study in 2025. The science works in mice. The gap between a mouse follicle and a human scalp is, unfortunately, significant.
May 15, 2026·about 2 months ago·Liam Foster
Clinical TrialsDHT2030 Cure
What Pyrilutamide Getting to Phase 3 Actually Means for Men With Hair Loss
Kintor Pharmaceutical's CB-03-01 successor has reached Phase 3 trials in the US and China. It is the most promising topical androgen receptor blocker in a generation, and the reason that matters goes beyond the obvious.
May 12, 2026·about 2 months ago·Dr. Maya Chen
Clinical TrialsDHTAntiandrogens
Clascoterone Phase 3 Data Is In, And It's More Complicated Than the Headlines Suggest
The first topical antiandrogen to complete Phase 3 for androgenetic alopecia showed meaningful hair density improvements, but the effect size tells a more nuanced story than its proponents acknowledge.
May 11, 2026·about 2 months ago·Dr. Maya Chen
CRISPRGene TherapyClinical Trials
CRISPR for Androgenetic Alopecia: The First Human Safety Data Has Arrived
A Phase 1 trial testing CRISPR-Cas9 to edit the androgen receptor gene in scalp follicles has reported its first safety data. No serious adverse events, and one unexpected finding worth paying attention to.
May 9, 2026·about 2 months ago·Dr. Maya Chen
MinoxidilClinical TrialsDHT
Oral Minoxidil at 1.25mg Is Working Differently to What Anyone Expected
Low-dose oral minoxidil has become one of the most prescribed off-label treatments in dermatology. The 2025 real-world data from 1,200 patients across three countries confirms the efficacy, and complicates the safety picture in ways worth understanding.
May 6, 2026·about 2 months ago·Liam Foster
JAK InhibitorsAlopecia AreataClinical Trials
Baricitinib Two-Year Follow-Up Data: What Actually Happens After the Trial Ends
The FDA approved baricitinib for severe alopecia areata in 2022. Two years later, the open-label extension data answers the question nobody asked in the initial trial: what happens when patients stop taking it?
May 5, 2026·2 months ago·Dr. Maya Chen
2030 CureWnt PathwayClinical Trials
Follica's Skin Disruption Protocol Is the Most Overlooked Hair Loss Treatment in Development
The idea that you can create new hair follicles by wounding the scalp sounds implausible. The science behind Follica's approach says otherwise, and their Phase 3 trial data has finally been submitted to the FDA.
May 4, 2026·2 months ago·Liam Foster
PRPClinical TrialsStem Cells
PRP for Hair Loss in 2025: The Definitive Meta-Analysis of 28 Randomised Trials
Platelet-rich plasma has been used for hair loss for over a decade. A 2025 meta-analysis of 28 randomised controlled trials finally answers whether it actually works, and if so, for whom and by how much.
May 3, 2026·2 months ago·Dr. Maya Chen
DHTClinical TrialsFinasteride
Dutasteride Mesotherapy vs Oral: A Head-to-Head Comparison the Field Has Been Waiting For
Intradermal injection of dutasteride directly into the scalp has been practiced by dermatologists for years. A 2025 randomised trial is the first to rigorously compare it to the oral version, and the results have implications for how we think about systemic drug exposure.
May 1, 2026·2 months ago·Dr. Maya Chen
ResearchClinical TrialsMinoxidil
Low-Level Laser Therapy for Hair Loss: What the 2025 Evidence Actually Shows
LLLT devices have been FDA-cleared for hair loss since 2007. Eighteen years later, a Cochrane-style systematic review has assembled the most rigorous evidence yet, and the picture is more nuanced than the device manufacturers suggest.
Apr 30, 2026·2 months ago·Liam Foster
Stem CellsExosomesClinical Trials
Stem Cell Conditioned Medium: The Quiet Treatment That's Building a Real Evidence Base
Rather than injecting stem cells directly, conditioned medium, the protein-rich fluid in which stem cells have grown, delivers the therapeutic signals without the cells themselves. The 2024-2025 trial data is genuinely promising.
Apr 29, 2026·2 months ago·Dr. Maya Chen
Hair TransplantClinical TrialsResearch
Robotic Hair Transplantation in 2025: What the Outcome Data Says About When It's Worth It
Robotic systems for hair transplantation have been marketed as precision improvements on manual FUE. A 2025 comparison study of 800 patients finally answers the question of whether that precision translates to better outcomes.
Apr 26, 2026·2 months ago·Dr. Maya Chen
FinasterideDHTClinical Trials
Finasteride at 10 Years: The Most Important Long-Term Safety Study Yet Published
A prospective 10-year study of finasteride 1mg for androgenetic alopecia, the longest rigorous follow-up ever conducted, has data on efficacy maintenance, sexual side effects, and cardiovascular outcomes that every user should know.
Apr 25, 2026·2 months ago·Liam Foster
MinoxidilResearchClinical Trials
Topical Caffeine vs Minoxidil: What a Proper Head-to-Head Trial Found
Caffeine-based hair products claim to rival minoxidil. A 2024 randomised controlled trial with 200 participants and an 6-month follow-up finally tested that claim properly.
Apr 24, 2026·2 months ago·Dr. Maya Chen
ResearchMinoxidilClinical Trials
Rosemary Oil vs Minoxidil: The 2024 Trial That Actually Held Up
A widely cited 2015 trial suggested rosemary oil matched 2% minoxidil for androgenetic alopecia. A more rigorous 2024 replication has now tested whether that finding survives proper methodology.
Mar 22, 2026·3 months ago·Dr. Maya Chen
ResearchTreatmentClinical Trials
Latanoprost and Bimatoprost for Hair Growth: A Prostaglandin Story Worth Following
Eye drops for glaucoma turned out to grow eyelashes. The mechanism, prostaglandin F2-alpha receptor agonism, has obvious implications for scalp hair, though the clinical data remains mixed.
Feb 7, 2026·5 months ago·Dr. Maya Chen
ResearchDHTClinical Trials
Setipiprant: The PGD2 Antagonist That Almost Was
Setipiprant blocks the prostaglandin D2 receptor implicated in androgenetic alopecia. The drug had a promising mechanism and a disappointing development path. Here's what happened.
Dec 28, 2025·6 months ago·Liam Foster
Alopecia AreataJAK InhibitorsClinical Trials
Alopecia Areata: Beyond JAK Inhibitors, What Else Is in the Pipeline
JAK inhibitors transformed alopecia areata treatment, but they're not the end of the story. Several other immune-modulating approaches are advancing through clinical trials.
Dec 9, 2025·7 months ago·Dr. Maya Chen
Hair TransplantResearchClinical Trials
Long-Term Outcomes After Hair Transplant: 10-Year Data Beyond Initial Results
Hair transplant results 12 months post-op look impressive. What they look like at 10 years tells a more complete story about lasting outcomes and ongoing native loss.
May 19, 2025·about 1 year ago·Dr. Maya Chen
ResearchClinical TrialsTreatment
Melatonin for Hair Loss: The Sleep Hormone With a Real but Modest Effect on Follicles
Topical melatonin sounds like wellness nonsense. The actual trial data shows a small but measurable effect on follicle density, with a coherent biological mechanism.
May 14, 2025·about 1 year ago·Liam Foster

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